Johannes F Fahrmann Selected Research

Neoplasms (Cancer)

10/2022	Blood-Based Biomarker Panel for Personalized Lung Cancer Risk Assessment.
5/2022	Mutational Activation of the NRF2 Pathway Upregulates Kynureninase Resulting in Tumor Immunosuppression and Poor Outcome in Lung Adenocarcinoma.
1/2022	CES2 sustains HNF4α expression to promote pancreatic adenocarcinoma progression through an epoxide hydrolase-dependent regulatory loop.
1/2022	SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas.
11/2021	A Blood-based Polyamine Signature Associated With MEN1 Duodenopancreatic Neuroendocrine Tumor Progression.
1/2021	Epigenetic Reprogramming Mediated by Maternal Diet Rich in Omega-3 Fatty Acids Protects From Breast Cancer Development in F1 Offspring.
11/2020	CES2 Expression in Pancreatic Adenocarcinoma Is Predictive of Response to Irinotecan and Is Associated With Type 2 Diabetes.
5/2020	Plasma-Derived Extracellular Vesicles Convey Protein Signatures that Reflect Pathophysiology in Lung and Pancreatic Adenocarcinomas.
2/2020	Proteome Profiling Uncovers an Autoimmune Response Signature That Reflects Ovarian Cancer Pathogenesis.
1/2020	Amino Acid Oncometabolism and Immunomodulation of the Tumor Microenvironment in Lung Cancer.

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Johannes F Fahrmann Research Topics

Disease

26	Neoplasms (Cancer) 10/2022 - 03/2013
9	Adenocarcinoma 01/2022 - 05/2015
7	Lung Neoplasms (Lung Cancer) 10/2022 - 11/2015
7	Adenocarcinoma of Lung 05/2022 - 11/2015
4	Pancreatic Neoplasms (Pancreatic Cancer) 01/2022 - 01/2019
3	Neoplasm Metastasis (Metastasis) 11/2021 - 01/2020
3	Ovarian Neoplasms (Ovarian Cancer) 02/2021 - 01/2020
2	Disease Progression 11/2021 - 01/2020
2	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 08/2021 - 01/2017
2	Triple Negative Breast Neoplasms 02/2021 - 01/2020
2	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2020
2	Type 2 Diabetes Mellitus (MODY) 11/2020 - 01/2015
2	Carcinogenesis 01/2020 - 01/2017
1	Neuroendocrine Tumors (Neuroendocrine Tumor) 11/2021
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Solitary Pulmonary Nodule 03/2016
1	Inflammation (Inflammations) 01/2016

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 10/2022 - 01/2016
9	Biomarkers (Surrogate Marker)IBA 10/2022 - 11/2015
5	PolyaminesIBA 11/2021 - 01/2017
5	LipidsIBA 01/2020 - 01/2015
4	AntigensIBA 10/2022 - 01/2020
3	Biological ProductsIBA 01/2022 - 01/2017
3	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2021 - 01/2013
3	ProteomeIBA 05/2020 - 01/2016
3	Neoplasm Antigens (Tumor Antigens)IBA 02/2020 - 01/2020
2	Messenger RNA (mRNA)IBA 01/2022 - 01/2020
2	Irinotecan (Camptosar)FDA LinkGeneric 01/2022 - 11/2020
2	AutoantibodiesIBA 02/2020 - 01/2020
2	AntioxidantsIBA 01/2016 - 05/2015
2	Fatty Acids (Saturated Fatty Acids)IBA 01/2015 - 03/2013
1	Keratin-19 (Keratin 19)IBA 10/2022
1	IgA receptor (protein B)IBA 10/2022
1	Carcinoembryonic AntigenIBA 10/2022
1	Surface-Active Agents (Surfactants)IBA 10/2022
1	KynurenineIBA 05/2022
1	Tryptophan (L-Tryptophan)FDA Link 05/2022
1	kynureninaseIBA 05/2022
1	EnzymesIBA 05/2022
1	Epoxide HydrolasesIBA 01/2022
1	ProdrugsIBA 01/2022
1	HydrolasesIBA 01/2022
1	Carboxylesterase (Hydrolase S)IBA 01/2022
1	Apoptosis Regulatory ProteinsIBA 01/2022
1	Serine (L-Serine)FDA Link 01/2022
1	B7-H1 AntigenIBA 01/2022
1	Thyroid Nuclear Factor 1IBA 01/2022
1	Rapeseed OilIBA 01/2021
1	Corn Oil (Oil, Corn)IBA 01/2021
1	9,10-Dimethyl-1,2-benzanthraceneIBA 01/2021
1	CarcinogensIBA 01/2021
1	folfirinoxIBA 11/2020
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 11/2020
1	Leucovorin (Folinic Acid)FDA Link 11/2020
1	Fluorouracil (Carac)FDA LinkGeneric 11/2020
1	Conditioned Culture MediaIBA 05/2020
1	Recombinant ProteinsIBA 02/2020
1	Immunoglobulins (Immunoglobulin)IBA 02/2020
1	Peptides (Polypeptides)IBA 02/2020
1	GlycosphingolipidsIBA 01/2020
1	5-hydroxymethylcytosineIBA 01/2020
1	Mitochondrial Proteins (Mitochondrial Protein)IBA 01/2020
1	VaccinesIBA 01/2020
1	2- (2'- (5- ethyl- 3,4- diphenyl- 1H- pyrazol- 1- yl)biphenyl- 3- yloxy)acetic acidIBA 01/2020
1	AmmoniaIBA 01/2020
1	Amino Acids FDA Link 01/2020
1	amsonic acid (DAS)IBA 01/2020
1	N',N''-diacetylspermineIBA 01/2020
1	Ligases (Synthetase)IBA 01/2020
1	Caveolin 1IBA 01/2020
1	DNA (Deoxyribonucleic Acid)IBA 01/2020
1	pyrimidineIBA 01/2020
1	Estrogen ReceptorsIBA 01/2020
1	Progesterone Receptors (Progesterone Receptor)IBA 01/2020
1	Carboplatin (JM8)FDA LinkGeneric 01/2020
1	SpermineIBA 01/2020
1	Spermine SynthaseIBA 01/2020
1	SphingolipidsIBA 01/2020
1	SphingomyelinsIBA 01/2020
1	CholesterolIBA 01/2020
1	CeramidesIBA 01/2020
1	Carbamyl Phosphate (Carbamoyl Phosphate)IBA 01/2020
1	Circulating Tumor DNAIBA 06/2018
1	Complement System Proteins (Complement)IBA 11/2017
1	Niacinamide (Nicotinamide)FDA LinkGeneric 01/2017
1	Phosphotransferases (Kinase)IBA 01/2017
1	phosphatidylethanolamineIBA 03/2016
1	5'-methylthioadenosineIBA 05/2015
1	XanthineIBA 05/2015
1	Uridine Diphosphate (UDP)IBA 05/2015
1	gamma-TocopherolIBA 05/2015
1	Dihydrouracil Dehydrogenase (NADP) (Dihydropyrimidine Dehydrogenase)IBA 05/2015
1	Cysteine (L-Cysteine)FDA Link 05/2015
1	purineIBA 05/2015
1	NucleotidesIBA 05/2015
1	Glucose (Dextrose)FDA LinkGeneric 05/2015

Therapy/Procedure

7	Therapeutics 11/2020 - 01/2013
1	Combination Drug Therapy (Combination Chemotherapy) 11/2020
1	Immunotherapy 01/2020
1	Immunomodulation 01/2020